Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6178509 | 0.82 | CA1 (0.46) | CRHR1CA1CA2CA9RAB9A | |
| SCHEMBL6179237 | 0.81 | ALDH1A1 (0.47) | CRHR1CA1CA2CA9RAB9A | |
| SCHEMBL6180141 | 0.79 | AKR1C3 (0.54) | RAB9ANPC1MAPTLMNAMAPK1 | |
| SCHEMBL6179386 | 0.77 | GAA (0.49) | CA1CA2CA9GAARAB9A | |
| SCHEMBL6179649 | 0.77 | CA1 (0.49) | CRHR1CA1CA2CA9GAA | |
| SCHEMBL8445623 | 0.69 | ALDH1A1 (0.48) | CRHR1GAAMAPTMAPK1KDM4E | |
| SCHEMBL8348984 | 0.69 | ALDH1A1 (0.51) | GAANPC1MAPTMAPK1KDM4E | |
| SCHEMBL14748179 | 0.66 | NR4A1 (0.65) | GAARAB9ANPC1MAPTLMNA | |
| SCHEMBL7719696 | 0.66 | GAA (0.68) | GAARAB9ANPC1MAPTLMNA | |
| SCHEMBL29703915 | 0.66 | ALDH1A1 (0.53) | CA1CA2CA9GAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1132387-B1 | PYRIMIDINYLBENZIMIDAZOLE AND TRIAZINYLBENZIMIDAZOLE DERIVATIVES AND AGRICULTURAL/HORTICULTURAL FUNGICIDES | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2005-09-28 | — | — | EP | claimed |