Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23421899 | 0.70 | KDM4E (0.46) | KDM4EL3MBTL1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL29661175 | 0.70 | KDM4E (0.46) | KDM4EL3MBTL1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL1022714 | 0.69 | KDM4E (0.45) | KDM4EL3MBTL1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL10734811 | 0.66 | MAPT (0.44) | KDM4EL3MBTL1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL29922862 | 0.65 | KDM4E (0.44) | KDM4EL3MBTL1CYP11B1CYP11B2 | |
| SCHEMBL16393588 | 0.65 | KDM4E (0.44) | KDM4EL3MBTL1CYP11B1CYP11B2 | |
| Benzene SCHEMBL28074857 | 0.63 | KDM4E (0.42) | KDM4EL3MBTL1CYP11B1CYP11B2 | |
| SCHEMBL20916020 | 0.63 | KDM4E (0.40) | KDM4EL3MBTL1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL23421759 | 0.63 | KDM4E (0.40) | KDM4EL3MBTL1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL3195815 | 0.63 | KDM4E (0.37) | KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 590 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9045569-B2 | Process of making modified metallocene catalyst, catalyst produced and use thereof | W. R. GRACE & CO.-CONN. (US) | 2015-06-02 | — | — | US | claimed |
| EP-1392741-B1 | PROCESS FOR PREPARING SUPPORTED TRANSITION METAL CATALYST SYSTEMS AND CATALYST SYSTEMS PREPARED THEREBY | GRACE W R & CO (US) | 2014-06-25 | — | — | EP | claimed |
| EP-2663400-A1 | PROCESS OF MAKING MODIFIED METALLOCENE CATALYST, CATALYST PRODUCED AND USE THEREOF | W. R. Grace & Co.-Conn (US) | 2013-11-20 | — | — | EP | claimed |
| US-20130289227-A1 | PROCESS OF MAKING MODIFIED METALLOCENE CATALYST, CATALYST PRODUCED AND USE THEREOF | W.R. GRACE & CO.-CONN (US) | 2013-10-31 | — | — | US | claimed |
| EP-1242478-B1 | METALLOCENE AND CONSTRAINED GEOMETRY CATALYST SYSTEMS EMPLOYING AGGLOMERATED METAL OXIDE/CLAY SUPPORT-ACTIVATOR AND METHOD OF THEIR PREPARATION | GRACE W R & CO (US) | 2012-12-05 | — | — | EP | claimed |
| WO-2012097146-A1 | PROCESS OF MAKING MODIFIED METALLOCENE CATALYST, CATALYST PRODUCED AND USE THEREOF | W. R. GRACE & CO.-CONN. (US) | 2012-07-19 | — | — | WO | claimed |
| US-7491672-B2 | Chemically-modified supports and supported catalyst systems prepared therefrom | INEOS EUROPE LIMITED (GB) | 2009-02-17 | — | — | US | claimed |
| US-20070105709-A1 | Chemically-modified supports and supported catalyst systems prepared therefrom | INEOS COMMERCIAL SERVICES UK LIMITED (GB) | 2007-05-10 | — | — | US | claimed |
| EP-1399491-B1 | SUPPORTED DUAL TRANSITION METAL CATALYST SYSTEMS | GRACE W R & CO (US) | 2006-08-23 | — | — | EP | claimed |
| US-6943224-B2 | Process for preparing supported transition metal catalyst systems and catalyst systems prepared thereby | W. R. GRACE & CO.-CONN. (US) | 2005-09-13 | — | — | US | claimed |
| WO-2001058969-A1 | CHEMICALLY-MODIFIED SUPPORTS AND SUPPORTED CATALYST SYSTEMS PREPARED THEREFROM | BP CHEMICALS LIMITED (GB) | 2001-08-16 | — | — | WO | claimed |
| WO-2001032721-A1 | METALLOCENE AND CONSTRAINED GEOMETRY CATALYST SYSTEMS EMPLOYING AGGLOMERATED METAL OXIDE/CLAY SUPPORT-ACTIVATOR AND METHOD OF THEIR PREPARATION | W. R. GRACE & CO.-CONN. (US) | 2001-05-10 | — | — | WO | claimed |
| WO-2000075152-A1 | DIMERIC GROUP 4 METALLOCENES IN +3 OXIDATION STATE | THE DOW CHEMICAL COMPANY (US) | 2000-12-14 | — | — | WO | claimed |
| EP-0977808-A1 | AMORPHOUS PROPYLENE-POLYENE COPOLYMERS AND COMPOSITIONS THEREOF | THE DOW CHEMICAL COMPANY (US) | 2000-02-09 | — | — | EP | claimed |
| WO-1998049229-A1 | AMORPHOUS PROPYLENE-POLYENE COPOLYMERS AND COMPOSITIONS THEREOF | THE DOW CHEMICAL COMPANY (US) | 1998-11-05 | — | — | WO | claimed |
| EP-0781299-B1 | SILYLIUM CATIONIC POLYMERIZATION ACTIVATORS FOR METALLOCENE COMPLEXES | DOW CHEMICAL CO (US) | 1998-09-09 | — | — | EP | claimed |
| US-5721183-A | ADDITION POLYMERIZATION CATALYSTS; INCLUDING GROUP 4 METAL COMPLEX | THE DOW CHEMICAL COMPANY (US) | 1998-02-24 | — | — | US | claimed |
| EP-0284359-B1 | 1,4-DISUBSTITUTED PIPERAZINE COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1992-01-08 | — | — | EP | claimed |
| US-4997836-A | Inhibitor of platelet activating factor | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-03-05 | — | — | US | claimed |
| US-4880809-A | HYPOTENSIVE AGENTS, AMIDE DERIVATIVES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-11-14 | — | — | US | claimed |