Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16393588 | 1.00 | KDM4E (0.44) | KDM4EL3MBTL1KDM1AACHEIDO1 | |
| SCHEMBL20418081 | 0.80 | KDM1A (0.36) | KDM4EL3MBTL1KDM1AACHEMAOA | |
| SCHEMBL23421899 | 0.76 | KDM4E (0.46) | KDM4EL3MBTL1KDM1AACHEIDO1 | |
| SCHEMBL29661175 | 0.76 | KDM4E (0.46) | KDM4EL3MBTL1KDM1AACHEIDO1 | |
| SCHEMBL7118363 | 0.74 | ADRA1A (0.43) | KDM1AIDO1CYP11B2CYP2D6 | |
| SCHEMBL7650679 | 0.71 | ACHE (0.46) | KDM4EL3MBTL1ACHEMAOAMAOB | |
| SCHEMBL14670557 | 0.71 | KDM1A (0.38) | KDM4EL3MBTL1KDM1AACHEMAOA | |
| SCHEMBL14669569 | 0.71 | KDM1A (0.38) | KDM4EL3MBTL1KDM1AACHEMAOA | |
| SCHEMBL1022714 | 0.71 | KDM4E (0.45) | KDM4EL3MBTL1KDM1AMAOBCYP11B2 | |
| SCHEMBL7639045 | 0.70 | KDM1A (0.37) | KDM4EL3MBTL1KDM1AACHEMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11492425-B2 | Metallocene catalyst compositions and polymerization process therewith | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2022-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11492425-B2 | Metallocene catalyst compositions and polymerization process therewith | TERT, MDM4, PCBP1 | KDM4E 1083/4885L3MBTL1 2321/4885KDM1A 2070/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.