Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 14/20 | 0.44 |
| ▸ | HTR2C | P28335 | 14/20 | 0.44 |
| ▸ | HTR2B | P41595 | 13/20 | 0.44 |
| ▸ | GSK3B | P49841 | 4/20 | 0.39 |
| ▸ | LATS1 | O95835 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL239258 | 1.00 | HTR2A (0.44) | HTR2AHTR2CHTR2BGSK3BLATS1 | |
| Hydrochloric Acid SCHEMBL5733483 | 0.98 | HTR2A (0.43) | HTR2AHTR2CHTR2BGSK3BLATS1 | |
| Tert-Butyl Formate SCHEMBL27606399 | 0.85 | GSK3B (0.38) | HTR2AHTR2CHTR2BGSK3B | |
| SCHEMBL6200965 | 0.81 | HTR2C (0.41) | HTR2AHTR2CHTR2B | |
| SCHEMBL13931360 | 0.81 | HTR2C (0.53) | HTR2AHTR2CHTR2B | |
| SCHEMBL4308092 | 0.77 | HTR2A (0.43) | HTR2AHTR2CHTR2B | |
| SCHEMBL4308089 | 0.77 | HTR2A (0.43) | HTR2AHTR2CHTR2B | |
| SCHEMBL4308087 | 0.77 | HTR2C (0.45) | HTR2AHTR2CHTR2B | |
| SCHEMBL2639565 | 0.77 | HTR2C (0.45) | HTR2AHTR2CHTR2B | |
| SCHEMBL6219727 | 0.75 | HTR2A (0.53) | HTR2AHTR2CHTR2BGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1529043-A1 | NOVEL PROCESS | Biovitrum AB (SE) | 2005-05-11 | — | — | EP | claimed |
| WO-2004000829-A1 | NOVEL PROCESS | BIOVITRUM AB (SE) | 2003-12-31 | — | — | WO | claimed |
| CN-100334082-C | Process for preparing 2-methylpiperazine derivatives | BIOVITRUM AB (SE) | 2007-08-29 | — | — | CN | disclosed |
| CN-100999501-A | Process for the preparation of 2-methyl piperazine derivatives | BIOVITRUM AB (SE) | 2007-07-18 | — | — | CN | disclosed |
| CN-1662523-A | Novel process | BIOVITRUM AB (SE) | 2005-08-31 | — | — | CN | disclosed |
| EP-1529043-A1 | NOVEL PROCESS | Biovitrum AB (SE) | 2005-05-11 | — | — | EP | disclosed |
| WO-2004000829-A1 | NOVEL PROCESS | BIOVITRUM AB (SE) | 2003-12-31 | — | — | WO | disclosed |