Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 3/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | DAO | P14920 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | DDO | Q99489 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31529969 | 0.75 | FLT3 (0.48) | FLT3CYP2A6KDM4EDAOMAPT | |
| SCHEMBL31529970 | 0.75 | FLT3 (0.48) | FLT3CYP2A6KDM4EDAOMAPT | |
| SCHEMBL27762933 | 0.71 | CYP2A6 (0.50) | FLT3CYP2A6KDM4EDAOMAPT | |
| SCHEMBL1654195 | 0.71 | FLT3 (0.42) | FLT3CYP2A6KDM4EDAOMAPT | |
| SCHEMBL28593629 | 0.70 | AOC3 (0.52) | FLT3CYP2A6KDM4EDAOMAPT | |
| SCHEMBL2728701 | 0.69 | FLT3 (0.67) | FLT3CYP2A6KDM4EDAOMAPT | |
| SCHEMBL28849651 | 0.69 | CYP2A6 (0.47) | FLT3CYP2A6KDM4EDAOMAPT | |
| SCHEMBL25305793 | 0.68 | GSTO1 (0.46) | FLT3CYP2A6KDM4EDAOMAPT | |
| SCHEMBL8609404 | 0.68 | KDM4E (0.45) | FLT3KDM4EDAOMAPTHPGD | |
| SCHEMBL3365468 | 0.67 | AOC3 (0.48) | FLT3CYP2A6KDM4EDAOMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1325490-C | Process for preparing high purity hydroxyindolylacetylglyoxylamides | ELBION AG (DE) | 2007-07-11 | — | — | CN | disclosed |
| CN-1671692-A | Method for producing highly pure hydroxy indolyl glyoxylic acid amides | ELBION AG (DE) | 2005-09-21 | — | — | CN | disclosed |
| EP-1525197-A1 | METHOD FOR PRODUCING HIGHLY PURE HYDROXY INDOLYL GLYOXYLIC ACID AMIDES | Elbion AG (DE) | 2005-04-27 | — | — | EP | disclosed |
| WO-2004013127-A1 | METHOD FOR PRODUCING HIGHLY PURE HYDROXY INDOLYL GLYOXYLIC ACID AMIDES | ELBION AG (DE) | 2004-02-12 | — | — | WO | disclosed |