Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.32 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6179890 | 0.93 | SMPD1 (0.38) | DNM1SMPD1 | |
| SCHEMBL6179279 | 0.86 | — | — | |
| SCHEMBL6181616 | 0.80 | TSHR (0.31) | TSHRSMN1; SMN2DNM1SMPD1 | |
| SCHEMBL7297339 | 0.80 | TSHR (0.40) | CA1CA2TSHRSMN1; SMN2DNM1 | |
| SCHEMBL611894 | 0.80 | — | — | |
| SCHEMBL6177172 | 0.78 | TSHR (0.30) | TSHRSMN1; SMN2DNM1 | |
| SCHEMBL6176438 | 0.78 | TSHR (0.30) | TSHRSMN1; SMN2DNM1 | |
| SCHEMBL6176443 | 0.78 | DNM1 (0.31) | CA1CA2TSHRSMN1; SMN2DNM1 | |
| SCHEMBL5708974 | 0.75 | DNM1 (0.38) | CA1CA2TSHRSMN1; SMN2DNM1 | |
| SCHEMBL5361 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945445-B9 | 1,5-BENZODIAZEPINE DERIVATIVES | ZERIA PHARM CO LTD (JP) | 2005-12-28 | — | — | EP | disclosed |
| EP-0945445-B1 | 1,5-BENZODIAZEPINE DERIVATIVES | ZERIA PHARM CO LTD (JP) | 2003-09-03 | — | — | EP | disclosed |
| US-6239131-B1 | WHICH HAVE GASTRIN AND/OR CCK-B (CHOLECYSTOKININ-B) RECEPTOR ANTAGONISM, USEFUL AS REMEDIES FOR GASTRIC ULCER AND GASTROINTESTINAL MOVEMENT DISORDER. | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-29 | — | — | US | disclosed |
| EP-0945445-A1 | 1,5-BENZODIAZEPINE DERIVATIVES | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |