Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SCN4A | P35499 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 5/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | XIAP | P98170 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | BIRC2 | Q13490 | 2/20 | 0.34 |
| ▸ | BIRC3 | Q13489 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6181742 | 1.00 | KDM4E (0.41) | KDM4EMAPK1SCN4AF2KCNH2 | |
| Hydrochloric Acid SCHEMBL6092133 | 0.99 | KDM4E (0.40) | KDM4EMAPK1SCN4AF2KCNH2 | |
| Hydrochloric Acid SCHEMBL6093429 | 0.99 | KDM4E (0.40) | KDM4EMAPK1SCN4AF2KCNH2 | |
| SCHEMBL6093041 | 0.88 | KDM4E (0.39) | KDM4EMAPK1SCN4AF2KCNH2 | |
| SCHEMBL6095258 | 0.88 | KDM4E (0.39) | KDM4EMAPK1SCN4AF2KCNH2 | |
| SCHEMBL6179483 | 0.86 | F2 (0.47) | F2 | |
| Hydrochloric Acid SCHEMBL6093262 | 0.85 | F2 (0.47) | F2 | |
| Hydrochloric Acid SCHEMBL6094489 | 0.85 | DPP4 (0.47) | F2DPP4 | |
| SCHEMBL6178104 | 0.85 | SCN4A (0.39) | KDM4EMAPK1SCN4AF2KCNH2 | |
| SCHEMBL6180622 | 0.85 | SCN4A (0.39) | KDM4EMAPK1SCN4AF2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1287018-B1 | THROMBIN INHIBITORS | LEK TOVARNA FARMACEVTSKIH (SI) | 2005-01-19 | — | — | EP | claimed |