Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 5/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.40 |
| ▸ | FAP | Q12884 | 3/20 | 0.39 |
| ▸ | SCN4A | P35499 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | AKT2 | P31751 | 1/20 | 0.36 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6094305 | 0.99 | DPP4 (0.41) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL6093274 | 0.90 | XIAP (0.40) | SCN4A | |
| SCHEMBL6179226 | 0.88 | DPP4 (0.46) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL6181089 | 0.88 | SCN5A (0.40) | DPP4DPP8DPP9DPP7FAP | |
| Hydrochloric Acid SCHEMBL6095357 | 0.88 | DPP4 (0.46) | DPP4DPP8DPP9DPP7FAP | |
| Hydrochloric Acid SCHEMBL7129856 | 0.88 | DPP4 (0.46) | DPP4DPP8DPP9DPP7FAP | |
| Hydrochloric Acid SCHEMBL6093146 | 0.87 | SCN5A (0.39) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL6180898 | 0.87 | SCN4A (0.38) | SCN4AKDR | |
| SCHEMBL6179716 | 0.85 | DPP4 (0.41) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL6184261 | 0.84 | SCN4A (0.56) | DPP4DPP8DPP9DPP7FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1287018-B1 | THROMBIN INHIBITORS | LEK TOVARNA FARMACEVTSKIH (SI) | 2005-01-19 | — | — | EP | claimed |