Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.36 |
| ▸ | XIAP | P98170 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6178144 | 0.87 | DPP4 (0.40) | SCN4AKDR | |
| Hydrochloric Acid SCHEMBL6094305 | 0.86 | DPP4 (0.41) | SCN4AKDR | |
| SCHEMBL6178779 | 0.86 | TACR1 (0.38) | SCN4ATACR1XIAPCASP1TAAR1 | |
| SCHEMBL6093274 | 0.86 | XIAP (0.40) | SCN4ATACR1XIAPTAAR1 | |
| SCHEMBL6184253 | 0.80 | SCN4A (0.41) | SCN4AMAPK1XIAPKDRPDGFRB | |
| SCHEMBL6179226 | 0.77 | DPP4 (0.46) | — | |
| Hydrochloric Acid SCHEMBL6095357 | 0.76 | DPP4 (0.46) | — | |
| Hydrochloric Acid SCHEMBL7129856 | 0.76 | DPP4 (0.46) | — | |
| SCHEMBL6180217 | 0.76 | SCN5A (0.38) | TACR1XIAPTAAR1 | |
| SCHEMBL6181089 | 0.76 | SCN5A (0.40) | KDRPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1287018-B1 | THROMBIN INHIBITORS | LEK TOVARNA FARMACEVTSKIH (SI) | 2005-01-19 | — | — | EP | claimed |