Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | NPC1 | O15118 | 6/20 | 0.38 |
| ▸ | RAB9A | P51151 | 6/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6176694 | 0.76 | MAOB (0.39) | ALDH1A1TDP1HSD17B10HPGDMAPT | |
| SCHEMBL3753518 | 0.73 | RAB9A (0.50) | ALDH1A1TDP1HPGDLMNAMAPT | |
| SCHEMBL13662606 | 0.73 | RAB9A (0.50) | ALDH1A1TDP1HPGDLMNAMAPT | |
| SCHEMBL7866168 | 0.73 | MCL1 (0.55) | ALDH1A1TDP1HPGDLMNAMAPT | |
| SCHEMBL5242917 | 0.72 | — | — | |
| SCHEMBL3746484 | 0.71 | NPC1 (0.35) | ALDH1A1TDP1HSD17B10HPGDLMNA | |
| SCHEMBL3747084 | 0.71 | NPC1 (0.38) | ALDH1A1TDP1HPGDLMNAMAPT | |
| SCHEMBL13659599 | 0.71 | MAPT (0.48) | ALDH1A1TDP1HPGDLMNAMAPT | |
| SCHEMBL5017261 | 0.70 | BCL2L1 (0.55) | ALDH1A1TDP1HPGDLMNAMAPT | |
| SCHEMBL7388558 | 0.70 | STING1 (0.48) | ALDH1A1TDP1HSD17B10LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1092716-B1 | Derivatives of benzothiophenes, benzofurans and indoles, method for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2005-02-16 | — | — | EP | disclosed |
| US-6302837-B1 | ANTICOAGULANTS | ADIR ET COMPAGNIE (FR) | 2001-10-16 | — | — | US | disclosed |
| EP-1092716-A2 | Derivatives of benzothiophenes, benzofurans and indoles, method for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2001-04-18 | — | — | EP | disclosed |