Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 5/20 | 0.47 |
| ▸ | CCKAR | P32238 | 1/20 | 0.44 |
| ▸ | CCKBR | P32239 | 1/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | XIAP | P98170 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6178120 | 0.88 | SCN9A (0.42) | SCN9ACCKARCCKBRAKT1ACE | |
| SCHEMBL6178646 | 0.86 | POLB (0.43) | SCN9ACCKARCCKBRACEPOLB | |
| SCHEMBL4701944 | 0.83 | SCN9A (0.50) | SCN9AXIAP | |
| SCHEMBL4702862 | 0.82 | SCN9A (0.53) | SCN9A | |
| SCHEMBL14084769 | 0.82 | SCN9A (0.53) | SCN9A | |
| SCHEMBL6175287 | 0.80 | SCN9A (0.43) | SCN9ACCKBRACEPOLB | |
| SCHEMBL4705050 | 0.78 | SCN9A (0.64) | SCN9ACCKARCCKBR | |
| SCHEMBL12345861 | 0.78 | SCN9A (0.64) | SCN9ACCKARCCKBR | |
| SCHEMBL14019266 | 0.78 | SCN9A (0.64) | SCN9ACCKARCCKBR | |
| SCHEMBL7421536 | 0.78 | PYGL (0.55) | SCN9ACCKBRACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945445-B9 | 1,5-BENZODIAZEPINE DERIVATIVES | ZERIA PHARM CO LTD (JP) | 2005-12-28 | — | — | EP | disclosed |
| EP-0945445-B1 | 1,5-BENZODIAZEPINE DERIVATIVES | ZERIA PHARM CO LTD (JP) | 2003-09-03 | — | — | EP | disclosed |
| US-6239131-B1 | WHICH HAVE GASTRIN AND/OR CCK-B (CHOLECYSTOKININ-B) RECEPTOR ANTAGONISM, USEFUL AS REMEDIES FOR GASTRIC ULCER AND GASTROINTESTINAL MOVEMENT DISORDER. | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-29 | — | — | US | disclosed |
| EP-0945445-A1 | 1,5-BENZODIAZEPINE DERIVATIVES | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |