Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7673466 | 0.88 | ITGB1 (0.66) | ITGB1ITGA4 | |
| SCHEMBL6177419 | 0.87 | ITGB1 (0.63) | ITGB1ITGA4 | |
| SCHEMBL21635811 | 0.80 | ITGB1 (0.56) | ITGB1ITGA4 | |
| SCHEMBL21635802 | 0.79 | ITGB1 (0.56) | ITGB1ITGA4 | |
| SCHEMBL7424447 | 0.79 | ITGB1 (0.71) | ITGB1ITGA4 | |
| SCHEMBL14528840 | 0.77 | ITGB1 (0.61) | ITGB1ITGA4 | |
| SCHEMBL6178527 | 0.77 | ITGB1 (0.51) | ITGB1ITGA4 | |
| SCHEMBL7024694 | 0.77 | ITGB1 (0.65) | ITGB1ITGA4 | |
| SCHEMBL7053184 | 0.76 | ITGB1 (0.69) | ITGB1ITGA4 | |
| SCHEMBL6179028 | 0.76 | ITGB1 (0.69) | ITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091943-B1 | NON-PEPTIDYL INHIBITORS OF VLA-4 DEPENDENT CELL BINDING USEFUL IN TREATING INFLAMMATORY, AUTOIMMUNE, AND RESPIRATORY DISEASES | PFIZER PROD INC (US) | 2005-11-30 | — | — | EP | disclosed |
| US-6355662-B1 | PEPTIDE AND NONPEPTIDES AUTOIMMUNE DISEASES, ANTIINFLAMMATORY AGENTS | PFIZER INC | 2002-03-12 | — | — | US | disclosed |
| US-6306887-B1 | AROMATIC UREAS, CARBAMATES AND TRIAMINONITRILES AND HETEROCYCLIC COMPOUNDS | PFIZER INC | 2001-10-23 | — | — | US | disclosed |
| EP-1091943-A1 | NON-PEPTIDYL INHIBITORS OF VLA-4 DEPENDENT CELL BINDING USEFUL IN TREATING INFLAMMATORY, AUTOIMMUNE, AND RESPIRATORY DISEASES | Pfizer Products Inc. (US) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000000477-A1 | NON-PEPTIDYL INHIBITORS OF VLA-4 DEPENDENT CELL BINDING USEFUL IN TREATING INFLAMMATORY, AUTOIMMUNE, AND RESPIRATORY DISEASES | PFIZER PRODUCTS INC. (US) | 2000-01-06 | — | — | WO | disclosed |