Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 16/20 | 0.80 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6180416 | 0.94 | GHSR (0.82) | GHSRSCN9ASLC6A4 | |
| SCHEMBL6177831 | 0.93 | GHSR (0.78) | GHSRSCN9A | |
| SCHEMBL6178796 | 0.90 | GHSR (0.86) | GHSR | |
| SCHEMBL6178394 | 0.90 | GHSR (0.76) | GHSRSCN9A | |
| SCHEMBL6179142 | 0.89 | GHSR (0.73) | GHSRSCN9A | |
| SCHEMBL6181326 | 0.89 | GHSR (0.85) | GHSR | |
| SCHEMBL6176866 | 0.89 | GHSR (0.73) | GHSR | |
| SCHEMBL6178198 | 0.89 | GHSR (0.75) | GHSR | |
| SCHEMBL6178202 | 0.89 | GHSR (0.75) | GHSRSCN9A | |
| SCHEMBL6179365 | 0.89 | GHSR (0.89) | GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1105376-B1 | OXINDOLE DERIVATIVES AS GROWTH HORMONE RELEASERS | SUMITOMO PHARMA (JP) | 2005-02-09 | — | — | EP | disclosed |
| US-6576656-B1 | Such as 1-(2-diethylaminoethyl)-4-trifluoromethyl-6-carbamoyl-3-hydroxy-3-(2 -chlorophenyl)oxindole; growth hormone releaser | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 2003-06-10 | — | — | US | disclosed |