Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 15/20 | 0.59 |
| ▸ | MYC | P01106 | 1/20 | 0.40 |
| ▸ | WDR5 | P61964 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | CCNE2 | O96020 | 9/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 9/20 | 0.34 |
| ▸ | CDK1 | P06493 | 7/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 7/20 | 0.34 |
| ▸ | CCNB2 | O95067 | 6/20 | 0.34 |
| ▸ | CDK4 | P11802 | 6/20 | 0.34 |
| ▸ | CCND1 | P24385 | 6/20 | 0.34 |
| ▸ | CCNB3 | Q8WWL7 | 6/20 | 0.34 |
| ▸ | CCND2 | P30279 | 4/20 | 0.34 |
| ▸ | CCND3 | P30281 | 4/20 | 0.34 |
| ▸ | CDK9 | P50750 | 2/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CDK7 | P50613 | 1/20 | 0.34 |
| ▸ | CCNH | P51946 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL960172 | 0.75 | CDK2 (1.00) | CDK2CCNE2CCNE1CDK1CCNB1 | |
| SCHEMBL3467464 | 0.74 | CDK2 (0.54) | CDK2MYCWDR5NOS1CCNE2 | |
| SCHEMBL9098198 | 0.73 | MYC (0.59) | CDK2MYCWDR5NOS1ALDH1A1 | |
| SCHEMBL3467465 | 0.73 | CDK2 (0.76) | CDK2CCNE2CCNE1CDK1CCNB1 | |
| SCHEMBL6198002 | 0.70 | CDK2 (0.60) | CDK2CCNE2CCNE1CDK1CCNB1 | |
| SCHEMBL6197997 | 0.70 | CDK2 (0.50) | CDK2MYCWDR5CCNE2CCNE1 | |
| SCHEMBL20583152 | 0.66 | CDK2 (0.59) | CDK2NOS1CCNE2CCNE1CDK1 | |
| SCHEMBL702948 | 0.66 | — | — | |
| SCHEMBL5725556 | 0.65 | CDK2 (0.45) | CDK2NOS1CDK9CDK7PIK3CG | |
| SCHEMBL5725589 | 0.65 | CDK2 (0.45) | CDK2NOS1CDK9CDK7PIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1303512-B1 | PROCESS FOR PREPARING ARYLACETYLAMINOTHIAZOLES | BRISTOL MYERS SQUIBB CO (US) | 2005-07-20 | — | — | EP | claimed |