Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 12/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 8/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 8/20 | 0.45 |
| ▸ | F2 | P00734 | 6/20 | 0.45 |
| ▸ | PLG | P00747 | 2/20 | 0.43 |
| ▸ | PROC | P04070 | 2/20 | 0.43 |
| ▸ | KLK1 | P06870 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6162881 | 0.91 | F10 (0.39) | F10PRSS1PRSS2PRSS3F2 | |
| Trifluoroacetic Acid SCHEMBL6179765 | 0.82 | F10 (0.52) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL7107211 | 0.77 | PRSS1 (0.44) | F10PRSS1PRSS2PRSS3F2 | |
| Trifluoroacetic Acid SCHEMBL7107447 | 0.74 | PTPRB (0.46) | F10PRSS1PRSS2PRSS3F2 | |
| Trifluoroacetic Acid SCHEMBL6162879 | 0.72 | PTPRB (0.46) | F10PRSS1PRSS2PRSS3F2 | |
| Trifluoroacetic Acid SCHEMBL7107207 | 0.72 | PTPRB (0.46) | F10PRSS1PRSS2PRSS3F2 | |
| Trifluoroacetic Acid SCHEMBL6167612 | 0.71 | F10 (0.63) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL6162409 | 0.70 | F10 (0.61) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL7107451 | 0.68 | PRSS1 (0.35) | F10PRSS1PRSS2PRSS3F2 | |
| Trifluoroacetic Acid SCHEMBL6166133 | 0.68 | F10 (0.64) | F10PRSS1PRSS2PRSS3F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1254136-A4 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG CHEM INVESTMENT LTD (KR) | 2005-06-01 | — | — | EP | disclosed |
| EP-1254136-A1 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG Chem Investment, Ltd. (KR) | 2002-11-06 | — | — | EP | disclosed |
| WO-2001055146-A1 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG CHEM INVESTMENT LTD. (KR) | 2001-08-02 | — | — | WO | disclosed |