Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 16/20 | 0.44 |
| ▸ | F10 | P00742 | 15/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 14/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 14/20 | 0.44 |
| ▸ | F2 | P00734 | 12/20 | 0.44 |
| ▸ | PLG | P00747 | 2/20 | 0.44 |
| ▸ | PROC | P04070 | 1/20 | 0.44 |
| ▸ | KLK1 | P06870 | 1/20 | 0.44 |
| ▸ | PLAT | P00750 | 1/20 | 0.42 |
| ▸ | F7 | P08709 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7107451 | 0.90 | PRSS1 (0.35) | PRSS1F10PRSS2PRSS3F2 | |
| Trifluoroacetic Acid SCHEMBL6179765 | 0.79 | F10 (0.52) | PRSS1F10PRSS2PRSS3F2 | |
| SCHEMBL6179772 | 0.77 | F10 (0.47) | PRSS1F10PRSS2PRSS3F2 | |
| SCHEMBL6162881 | 0.72 | F10 (0.39) | PRSS1F10PRSS2PRSS3F2 | |
| Trifluoroacetic Acid SCHEMBL6167612 | 0.71 | F10 (0.63) | PRSS1F10PRSS2PRSS3F2 | |
| SCHEMBL6162409 | 0.70 | F10 (0.61) | PRSS1F10PRSS2PRSS3F2 | |
| Trifluoroacetic Acid SCHEMBL6166404 | 0.69 | PRSS1 (0.53) | PRSS1F10PRSS2PRSS3F2 | |
| Trifluoroacetic Acid SCHEMBL7107447 | 0.69 | PTPRB (0.46) | PRSS1F10PRSS2PRSS3F2 | |
| Trifluoroacetic Acid SCHEMBL6164772 | 0.68 | PRSS1 (0.59) | PRSS1F10PRSS2PRSS3F2 | |
| Trifluoroacetic Acid SCHEMBL6166133 | 0.68 | F10 (0.64) | PRSS1F10PRSS2PRSS3F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030065176-A1 | Factor xa inhibitors with aryl-amidines and derivatives, and prodrugs thereof | LG CHEM INVESTMENT LTD. (KR) | 2003-04-03 | — | — | US | claimed |
| US-20030065176-A1 | Factor xa inhibitors with aryl-amidines and derivatives, and prodrugs thereof | LG CHEM INVESTMENT LTD. (KR) | 2003-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030065176-A1 | Factor xa inhibitors with aryl-amidines and derivatives, and prodrugs thereof | F2, F12, TFPI | PRSS1 43/4885F10 11/4885PRSS2 95/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.