Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 4/20 | 0.61 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.51 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6179859 | 1.00 | AGTR1 (0.61) | AGTR1ABCC3ABCC2 | |
| SCHEMBL6181485 | 0.86 | — | — | |
| SCHEMBL6181480 | 0.86 | — | — | |
| SCHEMBL6181764 | 0.83 | AGTR1 (0.51) | AGTR1 | |
| SCHEMBL6181752 | 0.83 | AGTR1 (0.51) | AGTR1 | |
| SCHEMBL6972699 | 0.80 | AGTR1 (0.72) | AGTR1 | |
| SCHEMBL6972690 | 0.80 | AGTR1 (0.72) | AGTR1 | |
| SCHEMBL6972507 | 0.79 | AGTR1 (0.84) | AGTR1 | |
| SCHEMBL6972501 | 0.79 | AGTR1 (0.84) | AGTR1 | |
| SCHEMBL6642074 | 0.78 | AGTR1 (0.81) | AGTR1ABCC3ABCC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000932-B9 | AROMATIC RING DERIVATIVES | FUJISAWA PHARMACEUTICAL CO (JP) | 2005-12-28 | — | — | EP | disclosed |
| EP-1000932-B1 | AROMATIC RING DERIVATIVES | FUJISAWA PHARMACEUTICAL CO (JP) | 2004-09-15 | — | — | EP | disclosed |
| US-6242474-B1 | SULFONYLCARBAMOYLALKYLIMIDAZOLE DERIVATIVES; ANTIDIABETIC AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-1000932-A1 | AROMATIC RING DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-05-17 | — | — | EP | disclosed |