Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 17/20 | 0.52 |
| ▸ | CCR5 | P51681 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | EDNRA | P25101 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5139335 | 0.83 | CCR5 (0.35) | CCR4CCR5MEN1PABPC1KMT2A | |
| SCHEMBL1733005 | 0.81 | CCR4 (0.53) | CCR4EDNRA | |
| SCHEMBL30915591 | 0.72 | EDNRA (0.37) | CCR4KMT2AEDNRA | |
| SCHEMBL4771395 | 0.72 | EDNRA (0.37) | CCR4KMT2AEDNRA | |
| SCHEMBL1733387 | 0.72 | CCR4 (0.52) | CCR4 | |
| SCHEMBL356058 | 0.72 | CCR4 (0.37) | CCR4MEN1KMT2A | |
| SCHEMBL1733274 | 0.72 | CCR4 (0.52) | CCR4EDNRA | |
| SCHEMBL8026505 | 0.71 | CCR4 (0.37) | CCR4EDNRA | |
| SCHEMBL7358178 | 0.71 | CCR4 (0.39) | CCR4EDNRA | |
| SCHEMBL30743762 | 0.71 | CCR4 (0.39) | CCR4EDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7410972-B2 | Compounds | ASTRAZENECA AB (SE) | 2008-08-12 | — | — | US | disclosed |
| EP-1458715-B1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2005-12-07 | — | — | EP | disclosed |
| EP-1458715-A1 | NOVEL COMPOUNDS | AstraZeneca AB (SE) | 2004-09-22 | — | — | EP | disclosed |
| WO-2003051870-A1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2003-06-26 | — | — | WO | disclosed |