Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 5/20 | 0.56 |
| ▸ | KCNQ2 | O43526 | 5/20 | 0.56 |
| ▸ | KCNE1 | P15382 | 4/20 | 0.56 |
| ▸ | KCNQ1 | P51787 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | GALR3 | O60755 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3146685 | 0.87 | KCNQ3 (0.60) | KCNQ3KCNQ2KCNE1KCNQ1MEN1 | |
| SCHEMBL7237944 | 0.86 | KCNQ3 (0.57) | KCNQ3KCNQ2KCNE1KCNQ1MEN1 | |
| SCHEMBL4717167 | 0.85 | KCNQ3 (0.60) | KCNQ3KCNQ2KCNE1KCNQ1MEN1 | |
| SCHEMBL7235460 | 0.85 | KCNQ3 (0.63) | KCNQ3KCNQ2KCNE1KCNQ1MEN1 | |
| Hydrochloric Acid SCHEMBL3131661 | 0.84 | BCAT2 (0.63) | KCNQ3KCNQ2KCNE1KCNQ1MEN1 | |
| Hydrochloric Acid SCHEMBL3140081 | 0.84 | KCNQ3 (0.59) | KCNQ3KCNQ2KCNE1KCNQ1MEN1 | |
| Hydrochloric Acid SCHEMBL3131676 | 0.84 | KCNQ3 (0.59) | KCNQ3KCNQ2KCNE1KCNQ1MEN1 | |
| SCHEMBL3143179 | 0.83 | KCNQ3 (0.58) | KCNQ3KCNQ2KCNE1KCNQ1MEN1 | |
| SCHEMBL3137030 | 0.83 | KCNQ3 (0.58) | KCNQ3KCNQ2KCNE1KCNQ1MEN1 | |
| SCHEMBL6179046 | 0.83 | KCNQ3 (0.58) | KCNQ3KCNQ2KCNE1KCNQ1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1066261-B1 | PYRIDINE DERIVATIVE AND PHARMACEUTICAL CONTAINING THE SAME | OTSUKA PHARMA CO LTD (JP) | 2005-11-23 | — | — | EP | disclosed |
| US-6511995-B1 | Inhibits collagen synthesis, which is useful for prophylaxis or treatment of fibrosis | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2003-01-28 | — | — | US | disclosed |