Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7972843 | 0.91 | EDNRA (0.62) | EDNRAEDNRB | |
| SCHEMBL31656332 | 0.91 | EDNRA (0.63) | EDNRAEDNRB | |
| SCHEMBL31656331 | 0.90 | EDNRA (0.73) | EDNRAEDNRB | |
| Clazosentan SCHEMBL29581324 | 0.88 | EDNRA (0.79) | EDNRAEDNRB | |
| Clazosentan SCHEMBL1983603 | 0.88 | EDNRA (0.79) | EDNRAEDNRB | |
| Clazosentan SCHEMBL29379450 | 0.88 | EDNRA (0.79) | EDNRAEDNRB | |
| Clazosentan SCHEMBL6974621 | 0.88 | EDNRA (0.78) | EDNRAEDNRB | |
| Clazosentan SCHEMBL29581457 | 0.88 | EDNRA (0.78) | EDNRAEDNRB | |
| Clazosentan SCHEMBL6974629 | 0.88 | EDNRA (0.78) | EDNRAEDNRB | |
| Clazosentan SCHEMBL26662037 | 0.88 | EDNRA (0.78) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0979822-B1 | Process for the preparation of 2-carbamoyl-pyridines | HOFFMANN LA ROCHE (CH) | 2005-11-30 | — | — | EP | claimed |