Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
| ▸ | PTGFR | P43088 | 1/20 | 0.45 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.45 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.45 |
| ▸ | PTGIR | P43119 | 1/20 | 0.45 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | VDR | P11473 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6180604 | 1.00 | TBXA2R (0.45) | TBXA2RPTGFRPTGER3PTGER2PTGIR | |
| SCHEMBL6185200 | 0.89 | TBXA2R (0.46) | TBXA2RPTGFRPTGER3PTGER2PTGIR | |
| SCHEMBL6185207 | 0.89 | TBXA2R (0.46) | TBXA2RPTGFRPTGER3PTGER2PTGIR | |
| SCHEMBL5672562 | 0.84 | HTT (0.36) | TBXA2RPTGFRPTGER3PTGER2PTGIR | |
| SCHEMBL5672570 | 0.84 | HTT (0.36) | TBXA2RPTGFRPTGER3PTGER2PTGIR | |
| SCHEMBL6180616 | 0.84 | TBXA2R (0.47) | TBXA2RPTGFRPTGER3PTGER2PTGIR | |
| SCHEMBL6180618 | 0.84 | TBXA2R (0.47) | TBXA2RPTGFRPTGER3PTGER2PTGIR | |
| SCHEMBL6181220 | 0.83 | VDR (0.50) | PPARGALDH1A1VDRLMNASMN1; SMN2 | |
| SCHEMBL5673070 | 0.82 | HDAC8 (0.39) | PPARGHDAC8 | |
| SCHEMBL5673821 | 0.82 | TBXA2R (0.35) | TBXA2RPTGFRPTGER3PTGER2PTGIR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000932-B9 | AROMATIC RING DERIVATIVES | FUJISAWA PHARMACEUTICAL CO (JP) | 2005-12-28 | — | — | EP | disclosed |
| EP-1000932-B1 | AROMATIC RING DERIVATIVES | FUJISAWA PHARMACEUTICAL CO (JP) | 2004-09-15 | — | — | EP | disclosed |
| US-6242474-B1 | SULFONYLCARBAMOYLALKYLIMIDAZOLE DERIVATIVES; ANTIDIABETIC AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-1000932-A1 | AROMATIC RING DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-05-17 | — | — | EP | disclosed |