Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6180598 | 0.93 | XIAP (0.48) | XIAP | |
| SCHEMBL6177504 | 0.93 | CCKBR (0.39) | XIAPCYP3A4 | |
| SCHEMBL6179477 | 0.90 | XIAP (0.44) | XIAP | |
| SCHEMBL6176902 | 0.89 | XIAP (0.46) | XIAPCYP3A4 | |
| SCHEMBL6177572 | 0.89 | SCN9A (0.40) | — | |
| SCHEMBL6177871 | 0.88 | ACE (0.39) | — | |
| SCHEMBL6178704 | 0.88 | SCN9A (0.41) | XIAPCYP3A4 | |
| SCHEMBL6180586 | 0.88 | XIAP (0.39) | XIAPCYP3A4 | |
| SCHEMBL6178130 | 0.88 | XIAP (0.43) | XIAPCYP3A4 | |
| SCHEMBL6178654 | 0.87 | XIAP (0.42) | XIAPCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945445-B9 | 1,5-BENZODIAZEPINE DERIVATIVES | ZERIA PHARM CO LTD (JP) | 2005-12-28 | — | — | EP | disclosed |
| EP-0945445-B1 | 1,5-BENZODIAZEPINE DERIVATIVES | ZERIA PHARM CO LTD (JP) | 2003-09-03 | — | — | EP | disclosed |
| US-6239131-B1 | WHICH HAVE GASTRIN AND/OR CCK-B (CHOLECYSTOKININ-B) RECEPTOR ANTAGONISM, USEFUL AS REMEDIES FOR GASTRIC ULCER AND GASTROINTESTINAL MOVEMENT DISORDER. | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-29 | — | — | US | disclosed |
| EP-0945445-A1 | 1,5-BENZODIAZEPINE DERIVATIVES | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |