Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 10/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | TACR3 | P29371 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5121718 | 1.00 | GRM5 (0.55) | GRM5ALDH1A1POLBHRH3TACR3 | |
| SCHEMBL6180672 | 0.86 | GRM5 (0.52) | GRM5ALDH1A1POLBTACR3NPC1 | |
| SCHEMBL5724695 | 0.83 | GRM5 (0.59) | GRM5ALDH1A1POLBTACR3NPC1 | |
| SCHEMBL7381273 | 0.82 | ALDH1A1 (0.68) | ALDH1A1POLBTACR3RAB9A | |
| SCHEMBL15092589 | 0.82 | GRM5 (0.58) | GRM5ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7341385 | 0.82 | SMN1; SMN2 (0.63) | HRH3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15092591 | 0.82 | GRM5 (0.58) | GRM5ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4703743 | 0.81 | GRM5 (0.54) | GRM5ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL4703742 | 0.81 | GRM5 (0.54) | GRM5ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL5121712 | 0.81 | GRM5 (0.54) | GRM5ALDH1A1POLBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1583741-A1 | 1-SUBSTITUTED-3-PYRROLIDINE DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | Ranbaxy Laboratories, Limited (IN) | 2005-10-12 | — | — | EP | disclosed |
| WO-2004056767-A1 | 1-SUBSTITUTED-3-PYRROLIDINE DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2004-07-08 | — | — | WO | disclosed |