SCHEMBL618073

SCHEMBL618073

OCC(O)CN(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNP P00491 2/20 0.53
POLB P06746 3/20 0.50
ALDH1A1 P00352 4/20 0.48
GAA P10253 2/20 0.48
MAPT P10636 2/20 0.48
MAPK1 P28482 1/20 0.48
TSHR P16473 4/20 0.44
NPC1 O15118 1/20 0.43
NPSR1 Q6W5P4 2/20 0.42
KDM4E B2RXH2 1/20 0.42
NPBWR1 P48145 1/20 0.42
KMT2A Q03164 1/20 0.42
MCHR1 Q99705 1/20 0.42
HTT P42858 1/20 0.40
DNM1 Q05193 1/20 0.40
CNR2 P34972 1/20 0.39
OPRM1 P35372 1/20 0.39
OPRD1 P41143 1/20 0.39
OPRK1 P41145 1/20 0.39
CYP1A2 P05177 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28594973 1.00 PNP (0.53) PNPPOLBALDH1A1GAAMAPT
SCHEMBL6227253 0.90 POLB (0.54) PNPPOLBALDH1A1GAAMAPT
SCHEMBL12192464 0.89 POLB (0.64) PNPPOLBALDH1A1GAAMAPT
Glycerin SCHEMBL27987155 0.88 CNR2 (0.46) PNPPOLBALDH1A1GAAMAPT
SCHEMBL21936369 0.88 POLB (0.53) PNPPOLBALDH1A1GAAMAPT
SCHEMBL10835683 0.86 POLB (0.54) PNPPOLBALDH1A1GAAMAPT
SCHEMBL7880359 0.85 PNP (0.44) PNPPOLBALDH1A1GAAMAPT
SCHEMBL14168226 0.85 ALDH1A1 (0.49) PNPPOLBALDH1A1GAAMAPT
SCHEMBL7193663 0.84 POLB (0.50) PNPPOLBALDH1A1GAAMAPT
SCHEMBL23512823 0.82 POLB (0.49) PNPPOLBALDH1A1GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113056265-A Farnesoin X receptor agonists and uses thereof 梅塔科林公司 2021-06-29 CN disclosed
CN-104558502-B HEUR thickener and preparation method thereof 罗门哈斯公司 2019-07-16 CN disclosed
EP-2894178-B1 HEUR THICKENER AND PROCESS FOR ITS PREPARATION ROHM & HAAS (US) 2017-09-27 EP disclosed
US-9663607-B2 HEUR thickener and process for its preparation ROHM AND HAAS COMPANY (US) 2017-05-30 US disclosed
US-20170130072-A1 HEUR THICKENER ROHM & HAAS (US) 2017-05-11 US disclosed
EP-3165547-A1 HEUR THICKENER Rohm and Haas Company (US) 2017-05-10 EP disclosed
EP-2894178-A1 HEUR Thickener and process for its preparation Rohm and Haas Company (US) 2015-07-15 EP disclosed
US-20150119525-A1 HEUR THICKENER AND PROCESS FOR ITS PREPARATION ROHM AND HAAS COMPANY 2015-04-30 US disclosed
CN-104558502-A HEUR THICKENER AND PROCESS FOR ITS PREPARATION ROHM & HAAS 2015-04-29 CN disclosed
US-8779055-B2 Hydrophobically modified alkylene oxide urethane polymer ROHM AND HAAS COMPANY (US) 2014-07-15 US disclosed
US-8779055-B2 Hydrophobically modified alkylene oxide urethane polymer ROHM AND HAAS COMPANY (US) 2014-07-15 US disclosed
US-8703684-B2 Aqueous lubricant IDEMITSU KOSAN CO., LTD. (JP) 2014-04-22 US disclosed
EP-2455412-B1 Hydrophobically modified alkylene oxide urethane polymer ROHM & HAAS (US) 2013-05-29 EP disclosed
EP-2594595-A1 Hydrophobically modified alkylene oxide urethane polymer Rohm and Haas Company (US) 2013-05-22 EP disclosed
US-20120130000-A1 HYDROPHOBICALLY MODIFIED ALKYLENE OXIDE URETHANE POLYMER ROHM AND HAAS COMPANY 2012-05-24 US disclosed
US-20120130000-A1 HYDROPHOBICALLY MODIFIED ALKYLENE OXIDE URETHANE POLYMER ROHM AND HAAS COMPANY 2012-05-24 US disclosed
EP-2455412-A1 Hydrophobically modified alkylene oxide urethane polymer Rohm and Haas Company (US) 2012-05-23 EP disclosed
US-20120040877-A1 AQUEOUS LUBRICANT IDEMITSU KOSAN CO., LTD. (JP) 2012-02-16 US disclosed
US-20100261813-A1 Thickener composition and method for thickening aqueous systems BOBSEIN BARRETT RICHARD 2010-10-14 US disclosed