Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6184242 | 0.93 | PTGS2 (0.57) | PTGS2PTGS1 | |
| SCHEMBL27554804 | 0.89 | PTGS2 (0.43) | PTGS2PTGS1 | |
| SCHEMBL7201017 | 0.84 | MDM2 (0.39) | PTGS2PTGS1 | |
| SCHEMBL8161919 | 0.84 | PTGS2 (0.38) | PTGS2PTGS1 | |
| SCHEMBL5322310 | 0.84 | PTGS2 (0.73) | PTGS2PTGS1 | |
| SCHEMBL7506364 | 0.83 | PTGS2 (0.38) | PTGS2PTGS1 | |
| SCHEMBL6170896 | 0.83 | PTGS2 (0.64) | PTGS2PTGS1 | |
| SCHEMBL6176550 | 0.83 | PTGS2 (0.55) | PTGS2PTGS1 | |
| SCHEMBL6168560 | 0.82 | PTGS2 (0.66) | PTGS2PTGS1 | |
| SCHEMBL6171284 | 0.82 | PTGS2 (0.70) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1045833-B1 | 2,3-SUBSTITUTED INDOLE COMPOUNDS AS COX-2 INHIBITORS | PFIZER (US) | 2005-11-02 | — | — | EP | disclosed |