Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 14/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | CALML3 | P27482 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4020719 | 0.89 | MAOA (0.42) | MAOAMAOBKCNH2CALML3CYP3A4 | |
| SCHEMBL4016060 | 0.83 | MAOA (0.44) | MAOAMAOBKCNH2CALML3CYP3A4 | |
| SCHEMBL4013878 | 0.82 | MAOA (0.39) | MAOAMAOBKCNH2CALML3CYP3A4 | |
| SCHEMBL6426220 | 0.76 | MAOA (0.60) | MAOAMAOBCALML3 | |
| SCHEMBL4016292 | 0.73 | MAOA (0.61) | MAOAMAOBKCNH2CYP3A4CYP2D6 | |
| SCHEMBL5792952 | 0.72 | MAOA (0.53) | MAOAMAOBCALML3 | |
| SCHEMBL4015683 | 0.71 | MAOA (0.53) | MAOAMAOBKCNH2CALML3CYP3A4 | |
| SCHEMBL4017450 | 0.71 | MAOA (0.59) | MAOAMAOBKCNH2CALML3CYP3A4 | |
| SCHEMBL4018740 | 0.70 | MAOA (0.47) | MAOAMAOBKCNH2CALML3CYP3A4 | |
| SCHEMBL4014935 | 0.69 | MAOA (0.44) | MAOAMAOBKCNH2CALML3CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1497286-A1 | 3-CYCLYL-5-(NITROGEN-CONTAINING 5-MEMBERED RING) METHYL-OXAZOLIDINONE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | Astrazeneca AB (SE) | 2005-01-19 | — | — | EP | claimed |
| WO-2003072575-A1 | 3-CYCLYL-5-(NITROGEN-CONTAINING 5-MEMBERED RING) METHYL-OXAZOLIDINONE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2003-09-04 | — | — | WO | claimed |