Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 1/20 | 0.59 |
| ▸ | NMBR | P28336 | 10/20 | 0.57 |
| ▸ | GRPR | P30550 | 9/20 | 0.55 |
| ▸ | TACR1 | P25103 | 6/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6181504 | 0.85 | CCKBR (0.53) | CCKBRNMBRGRPRTACR1 | |
| SCHEMBL6180815 | 0.85 | NMBR (0.74) | CCKBRNMBRGRPR | |
| SCHEMBL6251913 | 0.85 | NMBR (0.74) | CCKBRNMBRGRPR | |
| SCHEMBL8893642 | 0.84 | TACR1 (0.61) | CCKBRTACR1 | |
| SCHEMBL8893636 | 0.84 | TACR1 (0.61) | CCKBRTACR1 | |
| SCHEMBL8893860 | 0.83 | TACR1 (0.58) | CCKBRTACR1 | |
| SCHEMBL8893856 | 0.83 | TACR1 (0.58) | CCKBRTACR1 | |
| SCHEMBL6250373 | 0.82 | TACR1 (0.53) | CCKBRNMBRGRPRTACR1 | |
| SCHEMBL6250369 | 0.81 | NMBR (0.77) | NMBRGRPR | |
| SCHEMBL6183460 | 0.75 | NMBR (0.73) | CCKBRNMBRGRPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0920424-B1 | NON-PEPTIDE BOMBESIN RECEPTOR ANTAGONISTS | WARNER LAMBERT CO (US) | 2005-11-30 | — | — | EP | disclosed |
| US-6194437-B1 | ANTIDEPRESSANTS; ANTICANCER AGENTS; GASTROINTESTINAL DISORDERS; COGNITION ACTIVATORS | WARNER-LAMBERT COMPANY | 2001-02-27 | — | — | US | disclosed |
| EP-0920424-A1 | NON-PEPTIDE BOMBESIN RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1999-06-09 | — | — | EP | disclosed |
| WO-1998007718-A1 | NON-PEPTIDE BOMBESIN RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1998-02-26 | — | — | WO | disclosed |