Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19435586 | 0.87 | CLK4 (0.38) | MAPTTP53PKMSMN1; SMN2NPC1 | |
| SCHEMBL14656056 | 0.81 | NPC1 (0.52) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL6484311 | 0.81 | NPC1 (0.52) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL30186716 | 0.81 | NPC1 (0.52) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL2500804 | 0.79 | KMT2A (0.47) | MAPTLMNATP53NOTUMSMN1; SMN2 | |
| SCHEMBL969568 | 0.77 | — | — | |
| SCHEMBL10731993 | 0.77 | MAPT (0.46) | MAPTPKMNOTUMSMN1; SMN2NPC1 | |
| SCHEMBL4303322 | 0.77 | MEN1 (0.56) | MAPTTP53PKMSMN1; SMN2NPC1 | |
| SCHEMBL29522058 | 0.76 | — | — | |
| SCHEMBL5553224 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020165310-A1 | PYRIDINIUM COMPOUNDS AND THEIR USE AS HERBICIDES | SYNGENTA CROP PROTECTION AG (CH) | 2020-08-20 | — | — | WO | disclosed |
| WO-2020161162-A1 | HERBICIDAL PYRIDINIUM COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2020-08-13 | — | — | WO | disclosed |
| WO-2020161162-A1 | HERBICIDAL PYRIDINIUM COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2020-08-13 | — | — | WO | disclosed |
| CN-1199947-C | Process for preparing pyridine derivatives | SANKIO CHEMICAL CO LTD (JP) | 2005-05-04 | — | — | CN | disclosed |
| EP-1243579-B1 | PROCESS FOR THE PRODUCTION OF PYRIDINE DERIVATIVES | SANKIO CHEMICAL CO LTD (JP) | 2005-01-26 | — | — | EP | disclosed |
| CN-1402708-A | Process for production of pyridine derivs. | SANKIO CHEMICAL CO LTD (JP) | 2003-03-12 | — | — | CN | disclosed |
| US-6509469-B1 | Reacting 1,2,4-triazine compound with vinyl carboxylate | SANKIO CHEMICAL CO., LTD. (JP) | 2003-01-21 | — | — | US | disclosed |
| EP-1243579-A1 | PROCESS FOR THE PRODUCTION OF PYRIDINE DERIVATIVES | Sankio Chemical Co., Ltd. (JP) | 2002-09-25 | — | — | EP | disclosed |