Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.30 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6181756 | 1.00 | AOC3 (0.34) | AOC3NPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL9116742 | 0.85 | AOC3 (0.33) | AOC3NPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL9116733 | 0.85 | AOC3 (0.33) | AOC3NPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL9242386 | 0.85 | ACVRL1 (0.36) | NPC1RAB9AKDM4ESMN1; SMN2NPSR1 | |
| SCHEMBL9242392 | 0.85 | ACVRL1 (0.36) | NPC1RAB9AKDM4ESMN1; SMN2NPSR1 | |
| SCHEMBL6184434 | 0.84 | MAOB (0.34) | AOC3NPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL6184438 | 0.84 | MAOB (0.34) | AOC3NPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL6182434 | 0.82 | AOC3 (0.37) | AOC3NPC1RAB9AMTNR1AMTNR1B | |
| SCHEMBL6182438 | 0.82 | AOC3 (0.37) | AOC3NPC1RAB9AMTNR1AMTNR1B | |
| SCHEMBL1223403 | 0.71 | CYP11B1 (0.31) | ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1160244-B1 | Isoxazole derivatives and their use as herbicides | BAYER AGRICULTURE LTD (GB) | 2005-10-19 | — | — | EP | disclosed |
| EP-1160244-A1 | Isoxazole derivatives and their use as herbicides | RHONE-POULENC AGRICULTURE LIMITED (GB) | 2001-12-05 | — | — | EP | disclosed |
| US-5489570-A | PRE- OR POST-EMERGENCE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1996-02-06 | — | — | US | disclosed |
| EP-0636622-A1 | Isoxazole derivatives and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1995-02-01 | — | — | EP | disclosed |