Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.45 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | MCOLN2 | Q8IZK6 | 1/20 | 0.40 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.40 |
| ▸ | MCOLN1 | Q9GZU1 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6176194 | 0.94 | MEN1 (0.52) | MEN1KMT2ADRD4DRD2CHRM4 | |
| SCHEMBL6177540 | 0.91 | MEN1 (0.46) | MEN1KMT2ADRD4DRD2CHRM4 | |
| Cyclohexane SCHEMBL6179896 | 0.89 | MEN1 (0.57) | MEN1KMT2ADRD4DRD2CHRM4 | |
| Cyclohexane SCHEMBL6181887 | 0.86 | MEN1 (0.50) | MEN1KMT2ADRD4DRD2CHRM4 | |
| SCHEMBL6180627 | 0.84 | DRD4 (0.51) | MEN1KMT2ADRD4DRD2CHRM4 | |
| SCHEMBL6178285 | 0.83 | MEN1 (0.55) | MEN1KMT2ADRD4DRD2CHRM4 | |
| SCHEMBL6180433 | 0.82 | MEN1 (0.53) | MEN1KMT2ADRD4DRD2CHRM4 | |
| Cyclohexane SCHEMBL6180435 | 0.79 | MEN1 (0.48) | MEN1KMT2ADRD4DRD2CHRM4 | |
| SCHEMBL6179800 | 0.79 | MEN1 (0.53) | MEN1KMT2ADRD4DRD2CHRM4 | |
| SCHEMBL6177901 | 0.78 | MEN1 (0.50) | MEN1KMT2ADRD4DRD2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140830-B1 | ARYLPIPERIDINE AND ARYL-1,2,5,6-TETRAHYDROPYRIDINE AMIDE DERIVATIVES HAVING 5HT1A RECEPTOR ACTIVITY | WYETH CORP (US) | 2005-05-04 | — | — | EP | claimed |