Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 12/20 | 0.58 |
| ▸ | MAOA | P21397 | 5/20 | 0.55 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.55 |
| ▸ | PTPRB | P23467 | 1/20 | 0.55 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.55 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.55 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5512565 | 0.84 | MAOB (0.59) | MAOBMAOAPTPN2PTPN1PTPRB | |
| SCHEMBL10335673 | 0.83 | MAOB (0.65) | MAOBMAOAPTPN2PTPN1PTPRB | |
| SCHEMBL791923 | 0.82 | MAOB (0.69) | MAOBMAOAPTPN2PTPN1PTPRB | |
| SCHEMBL6573378 | 0.81 | L3MBTL1 (0.59) | MAOBMRGPRX4 | |
| SCHEMBL18797717 | 0.79 | MAOB (0.60) | MAOBMAOAPTPN2PTPN1PTPRB | |
| SCHEMBL18797716 | 0.79 | MAOB (0.60) | MAOBMAOAPTPN2PTPN1PTPRB | |
| SCHEMBL5369936 | 0.79 | MAOB (0.67) | MAOBMAOAPTPN2PTPN1PTPRB | |
| SCHEMBL19665980 | 0.79 | MAOB (0.60) | MAOBMAOAPTPN2PTPN1PTPRB | |
| SCHEMBL16948434 | 0.79 | MAOB (0.71) | MAOBMAOAPTPN2PTPN1PTPRB | |
| SCHEMBL19685525 | 0.78 | MAOB (0.63) | MAOBMAOAPTPN2PTPN1PTPRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1494989-A2 | COMPOUNDS THAT MODULATE PPAR ACTIVITY AND METHODS FOR THEIR PREPARATION | WARNER-LAMBERT COMPANY LLC (US) | 2005-01-12 | — | — | EP | disclosed |
| WO-2003084916-A2 | COMPOUNDS THAT MODULATE PPAR ACTIVITY AND METHODS FOR THEIR PREPARATION | WARNER-LAMBERT COMPANY LLC (US) | 2003-10-16 | — | — | WO | disclosed |