Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 9/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 9/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 8/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 8/20 | 0.46 |
| ▸ | F2 | P00734 | 7/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | PLAT | P00750 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6164497 | 0.92 | F10 (0.54) | F10PRSS1PRSS2PRSS3F2 | |
| Fluoroacetate SCHEMBL6182231 | 0.84 | TRPV1 (0.41) | TRPV1DHODHCNR1CREBBP | |
| SCHEMBL6171566 | 0.78 | GRM4 (0.54) | TRPV1DHODHCNR1CREBBP | |
| Trifluoroacetic Acid SCHEMBL6164502 | 0.77 | TRPV1 (0.44) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL7494748 | 0.76 | F10 (0.73) | F10PRSS1PRSS2PRSS3F2 | |
| Trifluoroacetic Acid SCHEMBL6203384 | 0.75 | F10 (0.76) | F10PRSS1PRSS2PRSS3F2 | |
| Trifluoroacetic Acid SCHEMBL6238656 | 0.73 | F10 (0.51) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL6840558 | 0.72 | F10 (0.58) | F10PRSS1F2 | |
| Acetic Acid SCHEMBL6839721 | 0.71 | F10 (0.57) | F10PRSS1F2 | |
| SCHEMBL18573213 | 0.68 | TRPV1 (0.71) | TRPV1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1254136-A4 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG CHEM INVESTMENT LTD (KR) | 2005-06-01 | — | — | EP | claimed |
| EP-1254136-A1 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG Chem Investment, Ltd. (KR) | 2002-11-06 | — | — | EP | claimed |
| WO-2001055146-A1 | FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF | LG CHEM INVESTMENT LTD. (KR) | 2001-08-02 | — | — | WO | claimed |