Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 1/20 | 0.43 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 16/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6184253 | 0.89 | SCN4A (0.41) | F2PDGFRBKDRDRD2DRD3 | |
| Hydrochloric Acid SCHEMBL6094528 | 0.85 | F2 (0.46) | SCN5ASCN3AF2F10PRSS1 | |
| SCHEMBL6179624 | 0.85 | F2 (0.41) | SCN5ASCN3AF2PRSS1 | |
| SCHEMBL6094199 | 0.84 | F2 (0.46) | SCN5ASCN3AF2F10PRSS1 | |
| SCHEMBL6094023 | 0.76 | F2 (0.52) | SCN5ASCN3AF2F10PRSS1 | |
| SCHEMBL6219378 | 0.76 | F2 (0.52) | SCN5ASCN3AF2F10PRSS1 | |
| SCHEMBL6181602 | 0.75 | SCN4A (0.61) | SCN5ASCN3AF2F10 | |
| SCHEMBL6180789 | 0.75 | SCN4A (0.40) | F2PDGFRBKDRDRD2DRD3 | |
| SCHEMBL6178343 | 0.75 | SCN4A (0.40) | F2PDGFRBKDRDRD2DRD3 | |
| SCHEMBL6094898 | 0.74 | F2 (0.50) | SCN5ASCN3AF2F10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1287018-B1 | THROMBIN INHIBITORS | LEK TOVARNA FARMACEVTSKIH (SI) | 2005-01-19 | — | — | EP | claimed |