⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2141813 | 0.61 | — | — | |
| SCHEMBL6699 | 0.56 | — | — | |
| SCHEMBL8019746 | 0.56 | — | — | |
| SCHEMBL2139113 | 0.55 | — | — | |
| SCHEMBL12493115 | 0.51 | — | — | |
| SCHEMBL14576740 | 0.51 | — | — | |
| SCHEMBL2139246 | 0.50 | — | — | |
| SCHEMBL596895 | 0.45 | — | — | |
| SCHEMBL486887 | 0.45 | — | — | |
| SCHEMBL2336640 | 0.44 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1503761-A1 | SUBSTITUTED PIPERAZINES AS MELANOCORTIN RECEPTOR LIGANDS | Neurocrine Biosciences, Inc. (US) | 2005-02-09 | — | — | EP | disclosed |
| WO-2003094918-A1 | SUBSTITUTED PIPERAZINE AS MELANOCORTIN RECEPTORS LIGANDS | NEUROCRINE BIOSCIENCES, INC. (US) | 2003-11-20 | — | — | WO | disclosed |