⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6181147 | 0.84 | — | — | |
| SCHEMBL6184980 | 0.82 | — | — | |
| SCHEMBL6183638 | 0.80 | PTGS2 (0.44) | — | |
| SCHEMBL6183650 | 0.80 | — | — | |
| SCHEMBL6182692 | 0.80 | — | — | |
| SCHEMBL6183377 | 0.79 | ATM (0.41) | — | |
| SCHEMBL6181206 | 0.70 | — | — | |
| SCHEMBL6184081 | 0.69 | — | — | |
| SCHEMBL6184427 | 0.67 | — | — | |
| SCHEMBL6184542 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1273582-B1 | Heterocyclo-alkylsulfonyl pyrazoles as anti-inflammatory/analgesic agents | PFIZER PROD INC (US) | 2005-06-29 | — | — | EP | claimed |
| US-6900230-B2 | Heterocyclo-alkylsulfonyl pyrazoles as anti-inflammatory/analgesic agents | PFIZER INC. (US) | 2005-05-31 | — | — | US | claimed |
| US-20030119836-A1 | Heterocyclo-alkylsulfonyl pyrazoles as anti-inflammatory/analgesic agents | SAKYA SUBAS M (US) | 2003-06-26 | — | — | US | claimed |
| EP-1273582-A1 | Heterocyclo-alkylsulfonyl pyrazoles as anti-inflammatory/analgesic agents | Pfizer Products Inc. (US) | 2003-01-08 | — | — | EP | claimed |
| EP-1273582-B1 | Heterocyclo-alkylsulfonyl pyrazoles as anti-inflammatory/analgesic agents | PFIZER PROD INC (US) | 2005-06-29 | — | — | EP | disclosed |
| US-6900230-B2 | Heterocyclo-alkylsulfonyl pyrazoles as anti-inflammatory/analgesic agents | PFIZER INC. (US) | 2005-05-31 | — | — | US | disclosed |
| US-20030119836-A1 | Heterocyclo-alkylsulfonyl pyrazoles as anti-inflammatory/analgesic agents | SAKYA SUBAS M (US) | 2003-06-26 | — | — | US | disclosed |
| EP-1273582-A1 | Heterocyclo-alkylsulfonyl pyrazoles as anti-inflammatory/analgesic agents | Pfizer Products Inc. (US) | 2003-01-08 | — | — | EP | disclosed |