Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ACACB | O00763 | 8/20 | 0.50 |
| ▸ | ACACA | Q13085 | 8/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6181851 | 1.00 | KDM4E (0.54) | KDM4EALDH1A1SMN1; SMN2HTTHPGD | |
| SCHEMBL6185100 | 0.91 | ACACB (0.61) | KDM4ESMN1; SMN2ACACBACACAMAPK1 | |
| SCHEMBL6183908 | 0.91 | ACACB (0.61) | KDM4ESMN1; SMN2ACACBACACAMAPK1 | |
| SCHEMBL6183528 | 0.84 | ACACB (0.64) | ACACBACACA | |
| SCHEMBL6183848 | 0.84 | ACACB (0.62) | ACACBACACA | |
| SCHEMBL6184683 | 0.83 | ACACB (0.61) | ACACBACACA | |
| SCHEMBL6181537 | 0.83 | ACACB (0.60) | ACACBACACA | |
| SCHEMBL6183523 | 0.81 | ACACB (0.48) | ACACBACACA | |
| SCHEMBL6490005 | 0.81 | ACACB (0.54) | ACACBACACA | |
| SCHEMBL6180226 | 0.81 | ACACB (0.58) | ACACBACACAGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1478437-B1 | ACC INHIBITORS | PFIZER PROD INC (US) | 2005-08-31 | — | — | EP | disclosed |