Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 15/20 | 0.61 |
| ▸ | ACACA | Q13085 | 15/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6185100 | 1.00 | ACACB (0.61) | ACACBACACAKDM4EGAAMAPK1 | |
| SCHEMBL6181851 | 0.91 | KDM4E (0.54) | ACACBACACAKDM4EGAAMAPK1 | |
| SCHEMBL6182735 | 0.91 | KDM4E (0.54) | ACACBACACAKDM4EGAAMAPK1 | |
| SCHEMBL6181391 | 0.87 | ACACB (0.65) | ACACBACACA | |
| SCHEMBL6184570 | 0.85 | ACACB (0.63) | ACACBACACA | |
| SCHEMBL6184710 | 0.85 | ACACB (0.66) | ACACBACACA | |
| SCHEMBL6184047 | 0.85 | ACACB (0.62) | ACACBACACA | |
| SCHEMBL6182331 | 0.83 | ACACB (0.60) | ACACBACACA | |
| SCHEMBL6185802 | 0.83 | ACACB (0.81) | ACACBACACA | |
| SCHEMBL6184997 | 0.83 | ACACB (0.69) | ACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1478437-B1 | ACC INHIBITORS | PFIZER PROD INC (US) | 2005-08-31 | — | — | EP | disclosed |