Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 15/20 | 0.69 |
| ▸ | ACACA | Q13085 | 15/20 | 0.69 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6183510 | 0.88 | ACACB (0.69) | ACACBACACAKDM2BCNR1MAPK1 | |
| SCHEMBL6183505 | 0.86 | ACACB (0.84) | ACACBACACAKDM2B | |
| SCHEMBL978699 | 0.85 | ACACB (0.74) | ACACBACACAKDM2B | |
| SCHEMBL6181556 | 0.85 | ACACB (0.80) | ACACBACACAKDM2B | |
| SCHEMBL2622325 | 0.85 | ACACB (0.83) | ACACBACACAKDM2B | |
| SCHEMBL976349 | 0.85 | ACACB (0.83) | ACACBACACAKDM2B | |
| SCHEMBL6185174 | 0.84 | ACACB (0.78) | ACACBACACAKDM2B | |
| SCHEMBL6184986 | 0.83 | ACACB (0.77) | ACACBACACAKDM2B | |
| SCHEMBL2622329 | 0.82 | ACACB (0.77) | ACACBACACAKDM2B | |
| SCHEMBL6491415 | 0.82 | ACACB (0.78) | ACACBACACAKDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1478437-B1 | ACC INHIBITORS | PFIZER PROD INC (US) | 2005-08-31 | — | — | EP | disclosed |