Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 14/20 | 0.80 |
| ▸ | ACACA | Q13085 | 14/20 | 0.80 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KDM2B | Q8NHM5 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6183505 | 0.93 | ACACB (0.84) | ACACBACACAKDM2BGAA | |
| SCHEMBL6186949 | 0.92 | ACACB (0.77) | ACACBACACAKDM2B | |
| SCHEMBL976349 | 0.92 | ACACB (0.83) | ACACBACACAKDM2B | |
| SCHEMBL2622325 | 0.92 | ACACB (0.83) | ACACBACACAKDM2B | |
| SCHEMBL6183307 | 0.89 | ACACB (0.72) | ACACBACACAKDM2BGAA | |
| SCHEMBL6183020 | 0.89 | ACACB (0.75) | ACACBACACAKDM2B | |
| SCHEMBL976549 | 0.89 | ACACB (1.00) | ACACBACACA | |
| SCHEMBL6491415 | 0.89 | ACACB (0.78) | ACACBACACAKDM2BGAA | |
| SCHEMBL3459079 | 0.89 | ACACB (1.00) | ACACBACACA | |
| SCHEMBL6185174 | 0.89 | ACACB (0.78) | ACACBACACAKDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6979741-B2 | Acetyl-CoA carboxylase inhibitors | PFIZER INC. (US) | 2005-12-27 | — | — | US | disclosed |
| EP-1478437-B1 | ACC INHIBITORS | PFIZER PROD INC (US) | 2005-08-31 | — | — | EP | disclosed |