Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 15/20 | 0.74 |
| ▸ | EDNRA | P25101 | 1/20 | 0.55 |
| ▸ | CCR5 | P51681 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6183896 | 0.90 | CCR4 (0.64) | CCR4CCR5KDM4EPOLBMEN1 | |
| SCHEMBL6181970 | 0.86 | CCR4 (0.76) | CCR4EDNRACCR5KDM4EPOLB | |
| SCHEMBL5106090 | 0.85 | CCR4 (1.00) | CCR4EDNRACCR5KDM4EPOLB | |
| SCHEMBL6183745 | 0.85 | CCR4 (0.70) | CCR4CCR5KDM4EPOLBMEN1 | |
| SCHEMBL5103307 | 0.82 | CCR4 (0.78) | CCR4EDNRACCR5MEN1KMT2A | |
| SCHEMBL6179652 | 0.82 | CCR4 (0.70) | CCR4EDNRACCR5KDM4EPOLB | |
| SCHEMBL6180658 | 0.82 | CCR4 (0.69) | CCR4KDM4EPOLBMEN1MAPT | |
| SCHEMBL5106594 | 0.81 | CCR4 (0.64) | CCR4EDNRACCR5 | |
| SCHEMBL6180252 | 0.80 | CCR4 (0.66) | CCR4EDNRACCR5KDM4EPOLB | |
| SCHEMBL5111672 | 0.80 | CCR4 (0.73) | CCR4CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1458715-B1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2005-12-07 | — | — | EP | disclosed |