Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 20/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1405598 | 0.94 | CETP (0.78) | CETP | |
| SCHEMBL6182520 | 0.89 | CETP (0.60) | CETP | |
| SCHEMBL3375812 | 0.89 | CETP (0.68) | CETP | |
| SCHEMBL3411380 | 0.87 | CETP (0.89) | CETP | |
| SCHEMBL992392 | 0.87 | CETP (0.89) | CETP | |
| SCHEMBL6588727 | 0.85 | CETP (0.77) | CETP | |
| SCHEMBL6588300 | 0.85 | CETP (0.69) | CETP | |
| SCHEMBL6587255 | 0.83 | CETP (0.73) | CETP | |
| SCHEMBL6587252 | 0.83 | CETP (0.73) | CETP | |
| Torcetrapib SCHEMBL10041443 | 0.83 | CETP (1.00) | CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1114031-B1 | 4-CARBOXYAMINO-2-SUBSTITUTED-1,2,3,4-TETRAHYDROQUINOLINES AS CETP INHIBITORS | PFIZER PROD INC (US) | 2005-06-15 | — | — | EP | claimed |