Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.54 |
| ▸ | TDP2 | O95551 | 1/20 | 0.54 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.54 |
| ▸ | PIM1 | P11309 | 6/20 | 0.52 |
| ▸ | PIM2 | Q9P1W9 | 5/20 | 0.52 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | GSK3B | P49841 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | NAT1 | P18440 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6183585 | 1.00 | MEN1 (0.60) | MEN1POLBKMT2AAKR1B1TDP2 | |
| SCHEMBL6184897 | 0.88 | PIK3CG (0.67) | MEN1POLBKMT2AAKR1B1TDP2 | |
| SCHEMBL6184899 | 0.88 | PIK3CG (0.67) | MEN1POLBKMT2AAKR1B1TDP2 | |
| SCHEMBL6187488 | 0.81 | AKR1B1 (0.76) | MEN1POLBKMT2AAKR1B1PIK3CG | |
| SCHEMBL6187848 | 0.81 | AKR1B1 (0.76) | MEN1POLBKMT2AAKR1B1PIM1 | |
| SCHEMBL6187852 | 0.81 | AKR1B1 (0.76) | MEN1POLBKMT2AAKR1B1PIM1 | |
| SCHEMBL6187486 | 0.81 | AKR1B1 (0.76) | MEN1POLBKMT2AAKR1B1PIK3CG | |
| SCHEMBL6473115 | 0.81 | HPGD (0.55) | MEN1POLBKMT2AAKR1B1PIK3CG | |
| SCHEMBL6473116 | 0.81 | HPGD (0.55) | MEN1POLBKMT2AAKR1B1PIK3CG | |
| SCHEMBL6992056 | 0.81 | PTPN1 (0.51) | AKR1B1PIK3CGPIM1PIM2PIM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1309575-B1 | BIPHENYL DERIVATIVES AND THEIR USE AS PPAR-GAMMA RECEPTOR ACTIVATORS | GALDERMA RES & DEV (FR) | 2005-06-08 | — | — | EP | disclosed |