Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 11/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.46 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6183585 | 0.81 | MEN1 (0.60) | HPGDPIK3CGPIM1PIM3PIM2 | |
| SCHEMBL6183587 | 0.81 | MEN1 (0.60) | HPGDPIK3CGPIM1PIM3PIM2 | |
| SCHEMBL6992046 | 0.75 | PTPN1 (0.50) | PTPN1HPGDPIM1PIM3PIM2 | |
| SCHEMBL6992052 | 0.75 | PTPN1 (0.50) | PTPN1HPGDPIM1PIM3PIM2 | |
| SCHEMBL6183335 | 0.73 | MAOA (0.56) | PTPN1HPGDPIK3CGPIM1PIM3 | |
| SCHEMBL6183331 | 0.73 | MAOA (0.56) | PTPN1HPGDPIK3CGPIM1PIM3 | |
| SCHEMBL6184899 | 0.73 | PIK3CG (0.67) | HPGDPIK3CGPIM1PIM3PIM2 | |
| SCHEMBL6184897 | 0.73 | PIK3CG (0.67) | HPGDPIK3CGPIM1PIM3PIM2 | |
| Phenylacetic Acid SCHEMBL6477210 | 0.73 | HPGD (0.60) | PTPN1HPGDPIM1PIM3PIM2 | |
| SCHEMBL6184404 | 0.71 | MEN1 (0.53) | PTPN1HPGDPIK3CGPIM1PIM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1309575-A1 | BIPHENYL DERIVATIVES AND THEIR USE AS PPAR-GAMMA RECEPTOR ACTIVATORS | Galderma Research & Development (FR) | 2003-05-14 | — | — | EP | disclosed |
| WO-2002012210-A9 | BIPHENYL DERIVATIVES AND THEIR USE AS PPAR-GAMMA RECEPTOR ACTIVATORS | GALDERMA RES & DEV (FR) | 2002-04-18 | — | — | WO | disclosed |
| WO-2002012210-A1 | BIPHENYL DERIVATIVES AND THEIR USE AS PPAR-GAMMA RECEPTOR ACTIVATORS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2002-02-14 | — | — | WO | disclosed |