Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 20/20 | 0.74 |
| ▸ | ABL1 | P00519 | 14/20 | 0.74 |
| ▸ | ABL2 | P42684 | 12/20 | 0.74 |
| ▸ | KDR | P35968 | 1/20 | 0.54 |
| ▸ | BCR | P11274 | 2/20 | 0.54 |
| ▸ | FYN | P06241 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6183085 | 0.92 | SRC (0.63) | SRCABL1ABL2KDRBCR | |
| SCHEMBL6188532 | 0.91 | SRC (0.73) | SRCABL1ABL2KDRBCR | |
| SCHEMBL6183491 | 0.88 | SRC (0.73) | SRCABL1ABL2BCRFYN | |
| SCHEMBL1657933 | 0.85 | SRC (1.00) | SRCABL1ABL2KDRBCR | |
| SCHEMBL30454364 | 0.85 | SRC (1.00) | SRCABL1ABL2KDRBCR | |
| SCHEMBL6184215 | 0.85 | SRC (0.73) | SRCABL1ABL2FYN | |
| SCHEMBL6183312 | 0.84 | SRC (0.73) | SRCABL1ABL2KDR | |
| SCHEMBL6183294 | 0.84 | SRC (0.63) | SRCABL1ABL2BCR | |
| SCHEMBL6184673 | 0.83 | SRC (0.60) | SRCABL1ABL2BCR | |
| SCHEMBL6184230 | 0.83 | SRC (0.68) | SRCABL1ABL2BCRFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1499594-B1 | PROCESS FOR THE PREPARATION OF 7-SUBSTITUTED-3-QUINOLINE AND 3-QUINOL-4-ONE CARBONITRILES | WYETH CORP (US) | 2005-08-17 | — | — | EP | claimed |