Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OTC | P00480 | 1/20 | 0.58 |
| ▸ | GSR | P00390 | 1/20 | 0.52 |
| ▸ | ARG2 | P78540 | 4/20 | 0.47 |
| ▸ | ARG1 | P05089 | 3/20 | 0.47 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.46 |
| ▸ | DDAH1 | O94760 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.43 |
| ▸ | NOS2 | P35228 | 3/20 | 0.42 |
| ▸ | NOS3 | P29474 | 2/20 | 0.42 |
| ▸ | NOS1 | P29475 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30331858 | 1.00 | OTC (0.58) | OTCGSRARG2ARG1NOD1 | |
| SCHEMBL5973446 | 0.85 | OTC (0.58) | OTCGSRARG2ARG1NOD1 | |
| SCHEMBL29486962 | 0.85 | OTC (0.58) | OTCGSRARG2ARG1NOD1 | |
| SCHEMBL358166 | 0.85 | OTC (0.58) | OTCGSRARG2ARG1NOD1 | |
| SCHEMBL12801966 | 0.85 | OTC (0.58) | OTCGSRARG2ARG1NOD1 | |
| SCHEMBL5974000 | 0.85 | OTC (0.58) | OTCGSRARG2ARG1NOD1 | |
| SCHEMBL6672850 | 0.85 | OTC (0.58) | OTCGSRARG2ARG1NOD1 | |
| SCHEMBL14682811 | 0.85 | OTC (0.58) | OTCGSRARG2ARG1NOD1 | |
| SCHEMBL18350239 | 0.85 | OTC (0.58) | OTCGSRARG2ARG1NOD1 | |
| SCHEMBL10005285 | 0.85 | OTC (0.58) | OTCGSRARG2ARG1NOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1521742-A1 | DIPHENYLAZETIDINONE DERIVATIVES FOR TREATING DISORDERS OF THE LIPID METABOLISM | AstraZeneca AB (SE) | 2005-04-13 | — | — | EP | disclosed |
| WO-2004005247-A1 | DIPHENYLAZETIDINONE DERIVATIVES FOR TREATING DISORDERS OF THE LIPID METABOLISM | ASTRAZENECA AB (SE) | 2004-01-15 | — | — | WO | disclosed |