SCHEMBL358166

SCHEMBL358166

NCC(=O)NCCCC[C@H](N)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
OTC P00480 1/20 0.58
GSR P00390 1/20 0.57
ARG2 P78540 4/20 0.47
ARG1 P05089 3/20 0.47
NOD1 Q9Y239 2/20 0.46
GNAI3 P08754 1/20 0.45
GNAO1 P09471 1/20 0.45
GNAI1 P63096 1/20 0.45
DDAH1 O94760 2/20 0.44
TDP1 Q9NUW8 1/20 0.43
DPP7 Q9UHL4 1/20 0.43
NOS3 P29474 2/20 0.42
NOS1 P29475 2/20 0.42
NOS2 P35228 2/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
TSHR P16473 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6672850 1.00 OTC (0.58) OTCGSRARG2ARG1NOD1
SCHEMBL3460656 1.00 OTC (0.58) OTCGSRARG2ARG1NOD1
SCHEMBL13043221 0.94 OTC (0.65) OTCGSRARG2ARG1NOD1
SCHEMBL21611913 0.93 OTC (0.53) OTCGSRARG2ARG1NOD1
SCHEMBL1768369 0.86 OTC (0.50) OTCGSRNOD1CYP1A2
SCHEMBL1768374 0.86 OTC (0.50) OTCGSRNOD1CYP1A2
SCHEMBL27841191 0.86 OTC (0.55) OTCGSRARG2ARG1NOD1
SCHEMBL12238274 0.86 OTC (0.55) OTCGSRARG2ARG1NOD1
SCHEMBL18924743 0.86 GSR (0.58) OTCGSRARG2ARG1NOD1
SCHEMBL5974000 0.85 OTC (0.58) OTCGSRARG2ARG1NOD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4720087-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR Zealand Pharma A/S (DK) 2026-04-08 EP disclosed
CN-113301920-B Complexes comprising a ligand, a spacer, a peptide linker and a biomolecule 安斯泰来制药株式会社 2025-01-14 CN disclosed
CN-119100961-A Preparation method of alkynylamide-mediated thiourea compound and application of alkynylamide-mediated thiourea compound in polypeptide cyclization 广州医科大学 2024-12-10 CN disclosed
WO-2024246269-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR ZEALAND PHARMA A/S (DK) 2024-12-05 WO disclosed
EP-4471048-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR Zealand Pharma A/S (DK) 2024-12-04 EP disclosed
US-20240390508-A1 HUMAN TRANSFERRIN RECEPTOR BINDING PEPTIDE-DRUG CONJUGATE TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2024-11-28 US disclosed
US-20240366775-A1 HUMAN TRANSFERRIN RECEPTOR BINDING ANTIBODY-PEPTIDE CONJUGATE PEPTIDREAM INC. (JP) 2024-11-07 US disclosed
EP-4393959-A1 HUMAN TRANSFERRIN RECEPTOR-BINDING ANTIBODY-PEPTIDE CONJUGATE PeptiDream Inc. (JP) 2024-07-03 EP disclosed
EP-4389893-A1 HUMAN TRANSFERRIN RECEPTOR BINDING PEPTIDE-DRUG CONJUGATE Takeda Pharmaceutical Company Limited (JP) 2024-06-26 EP disclosed
CN-118201966-A Human transferrin receptor binding antibody-peptide conjugates 肽梦想株式会社 2024-06-14 CN disclosed
WO-2003020901-A2 COMPOSITIONS AND METHODS RELATING TO PROSTATE SPECIFIC GENES AND PROTEINS DIADEXUS, INC. (US) 2003-03-13 WO disclosed
WO-2003020900-A2 COMPOSITIONS AND METHODS RELATING TO BREAST SPECIFIC GENES AND PROTEINS DIADEXUS, INC. (US) 2003-03-13 WO disclosed
WO-2003020953-A2 COMPOSITIONS AND METHODS RELATING TO COLON SPECIFIC GENES AND PROTEINS DIADEXUS, INC. (US) 2003-03-13 WO disclosed
US-20020102610-A1 Automated identification of peptides OXFORD GLYCOSCIENCES (UK) LTD. (GB) 2002-08-01 US disclosed
US-20020055186-A1 Detection of peptides OXFORD GLYCOSCIENCES (UK) LTD. 2002-05-09 US disclosed
WO-2002025287-A2 DETECTION OF PEPTIDES OXFORD GLYCOSCIENCES (UK) LTD. (GB) 2002-03-28 WO disclosed
WO-2002021139-A2 AUTOMATED IDENTIFICATION OF PEPTIDES OXFORD GLYCOSCIENCES (UK) LTD. (GB) 2002-03-14 WO disclosed
WO-1994018230-A1 INHIBITION OF HIV REPLICATION BY PEPTIDE-COPPER COMPLEXES PROCYTE CORPORATION (US) 1994-08-18 WO disclosed
EP-0077796-A1 NEW MEDICINE COMPRISED OF AN APROTININE-PLASMINE COMPLEX AND METHOD FOR THE PREPARATION OF SUCH NEW COMPLEX CHOAY S.A. (FR) 1983-05-04 EP disclosed
WO-1982003772-A1 NEW MEDICINE COMPRISED BY AN APROTININE-PLASMINE COMPLEX AND METHOD FOR THE PREPARATION OF SUCH NEW COMPLEX VAIREL EDMOND 1982-11-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240390508-A1 HUMAN TRANSFERRIN RECEPTOR BINDING PEPTIDE-DRUG CONJUGATE MUSK, TFRC, SLC7A1 OTC 2216/4885GSR 2231/4885ARG2 804/4885
US-20240366775-A1 HUMAN TRANSFERRIN RECEPTOR BINDING ANTIBODY-PEPTIDE CONJUGATE TFRC, MET, SLC7A1 OTC 2184/4885GSR 3980/4885ARG2 500/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.