Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | BPTF | Q12830 | 2/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.40 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.40 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.40 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5968363 | 1.00 | SIRT2 (0.43) | SIRT2BPTFKAT2BBRD9BRD4 | |
| SCHEMBL11018690 | 0.78 | MAPT (0.46) | SMN1; SMN2L3MBTL1KDM4EALDH1A1MAPT | |
| SCHEMBL5786752 | 0.76 | PIK3CA (0.42) | L3MBTL1ALDH1A1MAPTALOX15HSD17B10 | |
| SCHEMBL15994056 | 0.73 | MAOB (0.41) | SIRT2L3MBTL1KDM4ENPC1RAB9A | |
| SCHEMBL16596121 | 0.73 | MAOB (0.41) | SIRT2L3MBTL1KDM4ENPC1RAB9A | |
| SCHEMBL5968364 | 0.73 | SIRT2 (0.46) | SIRT2BPTFKAT2BBRD9BRD4 | |
| Hydrochloric Acid SCHEMBL15993984 | 0.72 | MAOB (0.42) | SIRT2L3MBTL1SLC6A2NPC1LMNA | |
| SCHEMBL1459468 | 0.71 | TAAR1 (0.54) | BPTFKAT2BBRD9HTR6TAAR1 | |
| SCHEMBL9559959 | 0.69 | MAPT (0.58) | SMN1; SMN2L3MBTL1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL1458404 | 0.69 | TAAR1 (0.52) | BPTFKAT2BBRD9HTR6TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1529038-A1 | BENZOTHIAZOLE DERIVATIVES HAVING BETA-2-ADRENORECEPTOR AGONIST ACTIVITY | Novartis AG (CH) | 2005-05-11 | — | — | EP | disclosed |
| WO-2004016601-A1 | BENZOTHIAZOLE DERIVATIVES HAVING BETA-2-ADRENORECEPTOR AGONIST ACTIVITY | NOVARTIS AG (CH) | 2004-02-26 | — | — | WO | disclosed |