Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.36 |
| ▸ | ESRRG | P62508 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | FCGR3B | O75015 | 1/20 | 0.35 |
| ▸ | FCGR1A | P12314 | 1/20 | 0.35 |
| ▸ | FCGR2A | P12318 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15994056 | 1.00 | MAOB (0.41) | MAOBMAOANPC1MTORRAB9A | |
| Hydrochloric Acid SCHEMBL15993984 | 0.99 | MAOB (0.42) | MAOBMAOANPC1MTORRAB9A | |
| SCHEMBL15994088 | 0.80 | MAPT (0.51) | MAOBMAOANPC1RAB9AKDM4E | |
| SCHEMBL4650493 | 0.76 | KDM4E (0.47) | RAB9AGAAKDM4EL3MBTL1 | |
| SCHEMBL2739352 | 0.74 | L3MBTL1 (0.48) | MAOBMAOANPC1RAB9AGAA | |
| SCHEMBL5968363 | 0.73 | SIRT2 (0.43) | NPC1RAB9ASIRT2GAAKDM4E | |
| SCHEMBL6183976 | 0.73 | SIRT2 (0.43) | NPC1RAB9ASIRT2GAAKDM4E | |
| SCHEMBL15994064 | 0.73 | MAOB (0.43) | MAOBMAOANPC1MTORRAB9A | |
| SCHEMBL11152408 | 0.72 | IDO1 (0.43) | ADRB2ADRB1KDM4EL3MBTL1 | |
| Hydrochloric Acid SCHEMBL15994134 | 0.72 | MAOB (0.44) | MAOBMAOANPC1MTORRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015044965-A4 | A PROCESS FOR PREPARATION OF MIRABEGRON AND ALPHA CRYSTALLINE FORM THEREOF | MEGAFINE PHARMA (P) LTD. (IN) | 2015-06-18 | — | — | WO | disclosed |
| WO-2015044965-A1 | A PROCESS FOR PREPARATION OF MIRABEGRON AND ALPHA CRYSTALLINE FORM THEREOF | MEGAFINE PHARMA (P) LTD. (IN) | 2015-04-02 | — | — | WO | disclosed |