Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 2/20 | 0.44 |
| ▸ | CCR4 | P51679 | 18/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6183754 | 0.85 | CCR4 (0.54) | EDNRACCR4CCR5 | |
| SCHEMBL6183556 | 0.85 | CCR4 (0.53) | EDNRACCR4CCR5 | |
| SCHEMBL6185920 | 0.83 | CCR4 (0.56) | EDNRACCR4CCR5 | |
| SCHEMBL6182007 | 0.80 | CCR4 (0.46) | EDNRACCR4CCR5 | |
| SCHEMBL6181508 | 0.80 | CCR5 (0.50) | CCR4CCR5 | |
| SCHEMBL6185560 | 0.79 | CCR4 (0.51) | CCR4CCR5 | |
| SCHEMBL6182695 | 0.79 | CCR4 (0.51) | EDNRACCR4CCR5 | |
| SCHEMBL6181837 | 0.78 | CCR5 (0.40) | CCR4CCR5 | |
| SCHEMBL6184018 | 0.77 | CCR4 (0.46) | EDNRACCR4CCR5 | |
| SCHEMBL6185446 | 0.77 | CCR4 (0.38) | CCR4CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1458715-B1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2005-12-07 | — | — | EP | claimed |