Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31485472 | 0.97 | — | — | |
| Trifluoromethanesulfonic Acid SCHEMBL9208517 | 0.75 | — | — | |
| SCHEMBL20552216 | 0.70 | — | — | |
| SCHEMBL19501343 | 0.69 | — | — | |
| SCHEMBL841057 | 0.67 | — | — | |
| SCHEMBL13352294 | 0.67 | CHRNA7 (0.32) | — | |
| SCHEMBL3483406 | 0.67 | — | — | |
| Water SCHEMBL31310133 | 0.65 | — | — | |
| Bromide SCHEMBL16968721 | 0.65 | — | — | |
| SCHEMBL4903183 | 0.63 | PTK2 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4545532-A1 | ADDITIVES FOR IMPROVED C-H FLUORINATION REACTIONS | Universität Regensburg (DE) | 2025-04-30 | — | — | EP | disclosed |
| CN-119504645-A | Method for synthesizing N- (acetamidomethyl) benzothiazine-4-ketone | 常州大学 | 2025-02-25 | — | — | CN | disclosed |
| CN-118772081-A | Method for preparing N-methyl-2, 3-dihydrobenzothiazine-4-ketone | 常州大学 | 2024-10-15 | — | — | CN | disclosed |
| US-9701684-B2 | Chiral fluorinating reagents | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2017-07-11 | — | — | US | disclosed |
| US-20150284401-A1 | CHIRAL FLUORINATING REAGENTS | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2015-10-08 | — | — | US | disclosed |
| EP-2914582-A2 | CHIRAL FLUORINATING REAGENTS | Isis Innovation Limited (GB) | 2015-09-09 | — | — | EP | disclosed |
| WO-2014068341-A2 | CHIRAL FLUORINATING REAGENTS | ISIS INNOVATION LIMITED (GB) | 2014-05-08 | — | — | WO | disclosed |
| EP-0946531-B1 | PROCESS FOR THE PREPARATION OF THIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2005-11-02 | — | — | EP | disclosed |
| US-6677457-B2 | HALOGENATION | SYNGENTA CROP PROTECTION, INC. | 2004-01-13 | — | — | US | disclosed |
| US-20030065191-A1 | Process for the preparation of thiazole derivatives | SYNGENTA CROP PROTECTION, INC. | 2003-04-03 | — | — | US | disclosed |
| US-6369233-B1 | MULTISTAGE REACTION TO FORM HALOSUBSTITUTED THIAZOLES WITH CHLORINATION | SYNGENTA CROP PROTECTION, INC. | 2002-04-09 | — | — | US | disclosed |
| US-6121455-A | CHLORINATION, SALT FORMATION | NOVARTIS CROP PROTECTION, INC. (US) | 2000-09-19 | — | — | US | disclosed |
| EP-0946531-A1 | PROCESS FOR THE PREPARATION OF THIAZOLE DERIVATIVES | Novartis AG (CH) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998027074-A1 | PROCESS FOR THE PREPARATION OF THIAZOLE DERIVATIVES | NOVARTIS AG (CH) | 1998-06-25 | — | — | WO | disclosed |
| EP-0478210-B1 | Fluorinated diazabicycloalkane derivatives | AIR PROD & CHEM (US) | 1995-11-15 | — | — | EP | disclosed |
| EP-0478210-A1 | Fluorinated diazabicycloalkane derivatives | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1992-04-01 | — | — | EP | disclosed |
| US-5086178-A | Fluorinated diazabicycloalkane derivatives | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1992-02-04 | — | — | US | disclosed |